## BTK inhibitors

Bruton Tyrosine Kinase (BTK) inhibitors inhibit the enzyme BTK, which plays a crucial role in oncogenic signaling and interactions with tumor microenvironment critical for proliferation, and survival of malignant B cells. Examples of BTK inhibitors include ibrutinib, zanubrutinib, and acalabrutinib.

### All Therapeutics

#### BTK inhibitors
- [Acalabrutinib](/content/therapeutics/btk-inhibitors/acalabrutinib/index.html)
- [Ibrutinib](/content/therapeutics/btk-inhibitors/ibrutinib/index.html)

### Articles of Interest

1. [Predictive factors of mortality in patients with hematological malignancies diagnosed with COVID-19](/content/medical-information/predictive-factors-of-mortality-in-patients-with-hematological-malignancies-diagnosed-with-covid-19/index.html)

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3. [Efficacy and safety of ibrutinib in RRMM](/content/medical-information/efficacy-and-safety-of-ibrutinib-in-rrmm/index.html)

*Published Mar 5, 2018*

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