# Immunocytokines

## Main Content

### Overview
Modakafusp alfa is a first-in-class antibody–cytokine fusion protein (immunocytokine) consisting of a human IgG1 and a cytokine engineered to target CD38, indicated for the treatment of relapsed/refractory multiple myeloma.

### Article
[Initial results in RRMM with modakafusp alfa: a first-in-class CD38-targeted immunocytokine](/content/medical-information/initial-results-in-rrmm-with-modakafusp-alfa-a-first-in-class-cd38-targeted-immunocytokine/index.html)

April 14, 2022

### Categories
- **Relapsed/refractory multiple myeloma**: [Learn more](/content/types/malignancies/relapsedrefractory-multiple-myeloma/index.html)

## Therapeutics

### Types of Therapeutics
- [Antibody recruiting molecules](/content/therapeutics/antibody-recruiting-molecules/index.html)
  - [BHV-1100](/content/therapeutics/antibody-recruiting-molecules/bhv-1100/index.html)

- [Antibody therapy](/content/therapeutics/antibody-therapy/index.html)
  - [Daratumumab](/content/therapeutics/antibody-therapy/daratumumab/index.html)
  - [Denosumab](/content/therapeutics/antibody-therapy/denosumab/index.html)

- [BCL-2 inhibitors](/content/therapeutics/bcl-2-inhibitors/index.html)
  - [Venetoclax](/content/therapeutics/bcl-2-inhibitors/venetoclax/index.html)

- [Biological therapy](/content/therapeutics/biological-therapy/index.html)
  - [Anakinra](/content/therapeutics/biological-therapy/anakinra/index.html)

- [Biphosphonates](/content/therapeutics/biphosphonates/index.html)
  - [Clodronate](/content/therapeutics/biphosphonates/clodronate/index.html)

- [Checkpoint inhibitors](/content/therapeutics/checkpoint-inhibitors/index.html)
  - [Atezolizumab](/content/therapeutics/checkpoint-inhibitors/atezolizumab/index.html)

- [Proteasome inhibitors](/content/therapeutics/proteasome-inhibitors/index.html)
  - [Bortezomib](/content/therapeutics/proteasome-inhibitors/bortezomib/index.html)

- [T-cell engagers](/content/therapeutics/t-cell-engagers/index.html)
  - [Blinatumomab](/content/therapeutics/t-cell-engagers/blinatumomab/index.html)

- [Vaccines](/content/therapeutics/vaccines/index.html)
  - [PVX-410](/content/therapeutics/vaccines/pvx-410/index.html)